There is a certain sense of deja-vu ahead of tonight's fixture, with this meeting the seventh meeting between these two sides in little over two years.
During that time Barca have had the upper hand with three victories and two draws, although Milan's solitary victory came at San Siro in Feburary as the Rossoneri recorded a famous 2-0 win.
Though the result ultimately proved immaterial, Barca will be aware of the potential threat posed by the Italians who are offered at a healthy looking 5/1 (6.00) with Paddy Power. Barca for their part can be backed at 4/7 (1.57) with the draw available at 3/1 (4.00).
It is of course difficult to back against Barca irrespective of their form and despite not scoring against Osasuna they should find the back of the net against a Milan side that has struggled to keep clean sheets, enjoying just three in their previous nine matches.
Barcelona to lead at the hour mark is offered at 4/5 (1.80)and that looks a decent enough option for investment.
This bet has a paid out in two of the last three meetings between the sides and looks like a decent bet in a market lacking overall appeal.